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3mdm

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===Thioperamide complex of Cytochrome P450 46A1===
===Thioperamide complex of Cytochrome P450 46A1===
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{{ABSTRACT_PUBMED_20667828}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:18621681</ref><references group="xtra"/>
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<ref group="xtra">PMID:20667828</ref><ref group="xtra">PMID:18621681</ref><references group="xtra"/>
[[Category: Cholesterol 24-hydroxylase]]
[[Category: Cholesterol 24-hydroxylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:38:21 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:20:22 2010''

Revision as of 07:10, 13 October 2010

Image:3mdm.png

Template:STRUCTURE 3mdm

Thioperamide complex of Cytochrome P450 46A1

Template:ABSTRACT PUBMED 20667828

About this Structure

3MDM is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mast N, Charvet C, Pikuleva IA, Stout CD. Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J Biol Chem. 2010 Oct 8;285(41):31783-95. Epub 2010 Jul 28. PMID:20667828 doi:10.1074/jbc.M110.143313
  • Mast N, White MA, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9546-51. Epub 2008 Jul 9. PMID:18621681

Page seeded by OCA on Wed Oct 13 10:20:22 2010

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