3mf5
From Proteopedia
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{{STRUCTURE_3mf5| PDB=3mf5 | SCENE= }} | {{STRUCTURE_3mf5| PDB=3mf5 | SCENE= }} | ||
===Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor=== | ===Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3mf5]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MF5 OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020584604</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase rna-dependent rna polymerase]] | [[Category: Transferase rna-dependent rna polymerase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:39:09 2010'' | ||
Revision as of 11:07, 26 July 2012
Contents |
Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
Template:ABSTRACT PUBMED 20584604
About this Structure
3mf5 is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Yang H, Hendricks RT, Arora N, Nitzan D, Yee C, Lucas MC, Yang Y, Fung A, Rajyaguru S, Harris SF, Leveque VJ, Hang JQ, Pogam SL, Reuter D, Tavares GA. Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4614-9. Epub 2010 Jun 8. PMID:20584604 doi:10.1016/j.bmcl.2010.06.008
