2j0f
From Proteopedia
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| - | [[Image:2j0f.jpg|left|200px]]<br /><applet load="2j0f" size=" | + | [[Image:2j0f.jpg|left|200px]]<br /><applet load="2j0f" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2j0f, resolution 2.31Å" /> | caption="2j0f, resolution 2.31Å" /> | ||
'''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''<br /> | '''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2J0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with TDR as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Tdr Binding Site For Chain C'>AC1</scene>. Full crystallographic information is available from [http:// | + | 2J0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TDR:'>TDR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0F OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:40:10 2008'' |
Revision as of 08:40, 3 February 2008
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STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN
Disease
Known disease associated with this structure: Mitochondrial neurogastrointestinal encephalomyopathy syndrome OMIM:[131222]
About this Structure
2J0F is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Thymidine phosphorylase, with EC number 2.4.2.4 Known structural/functional Site: . Full crystallographic information is available from OCA.
Page seeded by OCA on Sun Feb 3 10:40:10 2008
Categories: Homo sapiens | Single protein | Thymidine phosphorylase | Balzarini, J. | Bronckaers, A. | Liekens, S. | Omari, K.El. | Perez-Perez, M.J. | Stammers, D.K. | TDR | Angiogenesis | Chemotaxis | Developmental protein | Differentiation | Disease mutation | Glycosyltransferase | Growth factor | Htp | Human thymidine phosphorylase | Polymorphism | Transferase
