This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2j0f
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:2j0f.jpg|left|200px]]<br /><applet load="2j0f" size=" | + | [[Image:2j0f.jpg|left|200px]]<br /><applet load="2j0f" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2j0f, resolution 2.31Å" /> | caption="2j0f, resolution 2.31Å" /> | ||
'''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''<br /> | '''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''<br /> | ||
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2J0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with TDR as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Tdr Binding Site For Chain C'>AC1</scene>. Full crystallographic information is available from [http:// | + | 2J0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TDR:'>TDR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0F OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 30: | Line 30: | ||
[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:40:10 2008'' |
Revision as of 08:40, 3 February 2008
|
STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN
Disease
Known disease associated with this structure: Mitochondrial neurogastrointestinal encephalomyopathy syndrome OMIM:[131222]
About this Structure
2J0F is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Thymidine phosphorylase, with EC number 2.4.2.4 Known structural/functional Site: . Full crystallographic information is available from OCA.
Page seeded by OCA on Sun Feb 3 10:40:10 2008
Categories: Homo sapiens | Single protein | Thymidine phosphorylase | Balzarini, J. | Bronckaers, A. | Liekens, S. | Omari, K.El. | Perez-Perez, M.J. | Stammers, D.K. | TDR | Angiogenesis | Chemotaxis | Developmental protein | Differentiation | Disease mutation | Glycosyltransferase | Growth factor | Htp | Human thymidine phosphorylase | Polymorphism | Transferase
