2j3p
From Proteopedia
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| - | [[Image:2j3p.jpg|left|200px]]<br /><applet load="2j3p" size=" | + | [[Image:2j3p.jpg|left|200px]]<br /><applet load="2j3p" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2j3p, resolution 1.40Å" /> | caption="2j3p, resolution 1.40Å" /> | ||
'''CRYSTAL STRUCTURE OF RAT FGF1 AT 1.4 A'''<br /> | '''CRYSTAL STRUCTURE OF RAT FGF1 AT 1.4 A'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2J3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:So4 Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http:// | + | 2J3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3P OCA]. |
==Reference== | ==Reference== | ||
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[[Category: mitogen]] | [[Category: mitogen]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:41:12 2008'' |
Revision as of 08:41, 3 February 2008
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CRYSTAL STRUCTURE OF RAT FGF1 AT 1.4 A
Overview
Fibroblast growth factors (FGFs) constitute a family of 22 structurally, related heparin-binding polypeptides that are involved in the regulation, of cell growth, survival, differentiation and migration. Here, a 1.4 A, resolution X-ray structure of rat FGF1 is presented. Two molecules are, present in the asymmetric unit of the crystal and they coordinate a total, of five sulfate ions. The structures of human, bovine and newt FGF1 have, been published previously. Human and rat FGF1 are found to have very, similar structures.
About this Structure
2J3P is a Single protein structure of sequence from Rattus norvegicus with as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:17277441
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