3o1g
From Proteopedia
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| + | {{STRUCTURE_3o1g| PDB=3o1g | SCENE= }} | ||
| - | + | ===Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.=== | |
| - | Description: Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group. | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20843687}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20843687 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20843687}} | ||
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| + | ==About this Structure== | ||
| + | 3O1G is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O1G OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20843687</ref><references group="xtra"/> | ||
| + | [[Category: Cathepsin K]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Fradera, X.]] | ||
| + | [[Category: Uitdehaag, J C.M.]] | ||
| + | [[Category: Zeeland, M van.]] | ||
| + | [[Category: Bone]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: K protein from comp]] | ||
| + | [[Category: Ligand covalently bound to cys25]] | ||
| + | [[Category: Reversible covalent inhibitor]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:07:28 2010'' | ||
Revision as of 02:57, 6 October 2010
Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.
Template:ABSTRACT PUBMED 20843687
About this Structure
3O1G is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Finlay W, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Arbuckle W, Anderson M, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Jones P, Uitdehaag JC, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG. Bioorg Med Chem Lett. 2010 Aug 24. PMID:20843687 doi:10.1016/j.bmcl.2010.08.101
Page seeded by OCA on Wed Oct 6 06:07:28 2010
