2xnp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2xnp is ON HOLD Authors: Mas-Droux, C., Bayliss, R. Description: Structure of Nek2 bound to CCT244858 ''Page seeded by [http://oca.weizmann.ac.il/...) |
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- | + | [[Image:2xnp.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_2xnp", creates the "Structure Box" on the page. | ||
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+ | {{STRUCTURE_2xnp| PDB=2xnp | SCENE= }} | ||
- | + | ===STRUCTURE OF NEK2 BOUND TO CCT244858=== | |
- | Description: Structure of Nek2 bound to CCT244858 | ||
- | + | <!-- | |
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21366329}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21366329 is the PubMed ID number. | ||
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+ | {{ABSTRACT_PUBMED_21366329}} | ||
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+ | ==About this Structure== | ||
+ | [[2xnp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNP OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:21366329</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Non-specific serine/threonine protein kinase]] | ||
+ | [[Category: Bayliss, R.]] | ||
+ | [[Category: Mas-Droux, C.]] |
Revision as of 08:03, 30 March 2011
STRUCTURE OF NEK2 BOUND TO CCT244858
Template:ABSTRACT PUBMED 21366329
About this Structure
2xnp is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726