3npc

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[[Category: Type ii kinase inhibitor]]
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Revision as of 05:10, 1 September 2010

Image:3npc.png

Template:STRUCTURE 3npc

Crystal structure of JNK2 complexed with BIRB796

Template:ABSTRACT PUBMED 20655210

About this Structure

3NPC is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kuglstatter A, Ghate M, Tsing S, Villasenor AG, Shaw D, Barnett JW, Browner MF. X-ray crystal structure of JNK2 complexed with the p38alpha inhibitor BIRB796: insights into the rational design of DFG-out binding MAP kinase inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5217-20. Epub 2010 Jul 23. PMID:20655210 doi:10.1016/j.bmcl.2010.06.157

Page seeded by OCA on Wed Sep 1 09:18:21 2010

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