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2jal
From Proteopedia
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| - | [[Image:2jal.gif|left|200px]]<br /><applet load="2jal" size=" | + | [[Image:2jal.gif|left|200px]]<br /><applet load="2jal" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2jal, resolution 1.90Å" /> | caption="2jal, resolution 1.90Å" /> | ||
'''BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL'''<br /> | '''BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2JAL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with ACT, CA and YLL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] Known structural/functional Site: <scene name='pdbsite=NUC:Ca Binding Site For Chain B'>NUC</scene>. Full crystallographic information is available from [http:// | + | 2JAL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=YLL:'>YLL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] Known structural/functional Site: <scene name='pdbsite=NUC:Ca+Binding+Site+For+Chain+B'>NUC</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAL OCA]. |
==Reference== | ==Reference== | ||
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[[Category: polysaccharide degradation]] | [[Category: polysaccharide degradation]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:43:31 2008'' |
Revision as of 08:43, 3 February 2008
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL
Overview
The structural basis for beta-glucosidase inhibition by cyclophellitol is, demonstrated using X-ray crystallography, enzyme kinetics and mass, spectrometry.
About this Structure
2JAL is a Single protein structure of sequence from Thermotoga maritima with , and as ligands. Active as Beta-glucosidase, with EC number 3.2.1.21 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Structural basis for cyclophellitol inhibition of a beta-glucosidase., Gloster TM, Madsen R, Davies GJ, Org Biomol Chem. 2007 Feb 7;5(3):444-6. Epub 2006 Dec 14. PMID:17252125
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