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3kvn
From Proteopedia
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===Crystal structure of the full-length autotransporter EstA from Pseudomonas aeruginosa=== | ===Crystal structure of the full-length autotransporter EstA from Pseudomonas aeruginosa=== | ||
| + | {{ABSTRACT_PUBMED_20060837}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/ESTA_PSEAE ESTA_PSEAE]] Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes is unclear. In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents. Also shows relatively high activity towards beta-naphthyl butyrate, whereas its activities towards triacylglycerols and acyls-CoA are negligible.<ref>PMID:17631636</ref> <ref>PMID:20931591</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3kvn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVN OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020060837</ref><references group="xtra"/><references/> |
[[Category: Carboxylesterase]] | [[Category: Carboxylesterase]] | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
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[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:08:30 2010'' | ||
Revision as of 20:41, 4 April 2013
Contents |
Crystal structure of the full-length autotransporter EstA from Pseudomonas aeruginosa
Template:ABSTRACT PUBMED 20060837
Function
[ESTA_PSEAE] Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes is unclear. In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents. Also shows relatively high activity towards beta-naphthyl butyrate, whereas its activities towards triacylglycerols and acyls-CoA are negligible.[1] [2]
About this Structure
3kvn is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- van den Berg B. Crystal structure of a full-length autotransporter. J Mol Biol. 2010 Feb 26;396(3):627-33. Epub 2010 Jan 11. PMID:20060837 doi:10.1016/j.jmb.2009.12.061
- ↑ Wilhelm S, Gdynia A, Tielen P, Rosenau F, Jaeger KE. The autotransporter esterase EstA of Pseudomonas aeruginosa is required for rhamnolipid production, cell motility, and biofilm formation. J Bacteriol. 2007 Sep;189(18):6695-703. Epub 2007 Jul 13. PMID:17631636 doi:10.1128/JB.00023-07
- ↑ Lescic Asler I, Ivic N, Kovacic F, Schell S, Knorr J, Krauss U, Wilhelm S, Kojic-Prodic B, Jaeger KE. Probing enzyme promiscuity of SGNH hydrolases. Chembiochem. 2010 Oct 18;11(15):2158-67. doi: 10.1002/cbic.201000398. PMID:20931591 doi:10.1002/cbic.201000398
