3m9q

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{{STRUCTURE_3m9q| PDB=3m9q | SCENE= }}
{{STRUCTURE_3m9q| PDB=3m9q | SCENE= }}
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===Drosophila MSL3 chromodomain===
===Drosophila MSL3 chromodomain===
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{{ABSTRACT_PUBMED_20657587}}
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==Function==
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[[http://www.uniprot.org/uniprot/MSL3_DROME MSL3_DROME]] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.<ref>PMID:7768187</ref>
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{{ABSTRACT_PUBMED_20657587}}
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==About this Structure==
==About this Structure==
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3M9Q is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9Q OCA].
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[[3m9q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9Q OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20657587</ref><references group="xtra"/>
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<ref group="xtra">PMID:020657587</ref><references group="xtra"/><references/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Huang, P.]]
[[Category: Huang, P.]]
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[[Category: Msl3]]
[[Category: Msl3]]
[[Category: Transcription upregulation]]
[[Category: Transcription upregulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:11:05 2010''
 

Revision as of 23:16, 10 April 2013

Template:STRUCTURE 3m9q

Contents

Drosophila MSL3 chromodomain

Template:ABSTRACT PUBMED 20657587

Function

[MSL3_DROME] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.[1]

About this Structure

3m9q is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Kim D, Blus BJ, Chandra V, Huang P, Rastinejad F, Khorasanizadeh S. Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nat Struct Mol Biol. 2010 Aug;17(8):1027-9. Epub 2010 Jul 25. PMID:20657587 doi:10.1038/nsmb.1856
  1. ↑ Gorman M, Franke A, Baker BS. Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila. Development. 1995 Feb;121(2):463-75. PMID:7768187

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