3nr4

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[[Image:3nr4.png|left|200px]]
 
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{{STRUCTURE_3nr4| PDB=3nr4 | SCENE= }}
{{STRUCTURE_3nr4| PDB=3nr4 | SCENE= }}
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===Pyrabactin-bound PYL2===
===Pyrabactin-bound PYL2===
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{{ABSTRACT_PUBMED_20630864}}
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==Function==
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[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
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{{ABSTRACT_PUBMED_20630864}}
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==About this Structure==
==About this Structure==
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3NR4 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR4 OCA].
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[[3nr4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NR4 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20630864</ref><references group="xtra"/>
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<ref group="xtra">PMID:020630864</ref><references group="xtra"/><references/>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Yan, N.]]
[[Category: Yan, N.]]
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[[Category: Pyrabactin]]
[[Category: Pyrabactin]]
[[Category: Receptor]]
[[Category: Receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:14:13 2010''
 

Revision as of 11:39, 24 April 2013

Template:STRUCTURE 3nr4

Contents

Pyrabactin-bound PYL2

Template:ABSTRACT PUBMED 20630864

Function

[PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.[1] [2]

About this Structure

3nr4 is a 3 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

  • Yuan X, Yin P, Hao Q, Yan C, Wang J, Yan N. Single Amino Acid Alteration between Valine and Isoleucine Determines the Distinct Pyrabactin Selectivity by PYL1 and PYL2. J Biol Chem. 2010 Sep 10;285(37):28953-8. Epub 2010 Jul 14. PMID:20630864 doi:10.1074/jbc.M110.160192
  1. Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jensen DR, Yong EL, Volkman BF, Cutler SR, Zhu JK, Xu HE. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature. 2009 Dec 3;462(7273):602-8. PMID:19898420 doi:10.1038/nature08613
  2. Yin P, Fan H, Hao Q, Yuan X, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec;16(12):1230-6. Epub 2009 Nov 5. PMID:19893533 doi:10.1038/nsmb.1730

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