3fhe
From Proteopedia
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===Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.=== | ===Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3fhe]] is a 1 chain structure of [[Leukotriene A4 Hydrolase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FHE OCA]. | |
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| + | ==See Also== | ||
| + | *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019950900</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Davies, D R.]] | [[Category: Davies, D R.]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Structure based drug design]] | [[Category: Structure based drug design]] | ||
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Revision as of 02:30, 27 July 2012
Contents |
Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
Template:ABSTRACT PUBMED 19950900
About this Structure
3fhe is a 1 chain structure of Leukotriene A4 Hydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sandanayaka V, Mamat B, Mishra RK, Winger J, Krohn M, Zhou LM, Keyvan M, Enache L, Sullins D, Onua E, Zhang J, Halldorsdottir G, Sigthorsdottir H, Thorlaksdottir A, Sigthorsson G, Thorsteinnsdottir M, Davies DR, Stewart LJ, Zembower DE, Andresson T, Kiselyov AS, Singh J, Gurney ME. Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis. J Med Chem. 2009 Dec 1. PMID:19950900 doi:10.1021/jm900838g
