3o50

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==About this Structure==
==About this Structure==
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3O50 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O50 OCA].
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[[3o50]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O50 OCA].
==Reference==
==Reference==
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[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Huang, X.]]
[[Category: Huang, X.]]
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[[Category: Auroraa]]
 
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[[Category: Kinase domain]]
 
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[[Category: Transferase]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:51:09 2010''
 

Revision as of 08:12, 6 April 2011

Template:STRUCTURE 3o50

Crystal structure of benzamide 9 bound to AuroraA

Template:ABSTRACT PUBMED 20684549

About this Structure

3o50 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cee VJ, Schenkel LB, Hodous BL, Deak HL, Nguyen HN, Olivieri PR, Romero K, Bak A, Be X, Bellon S, Bush TL, Cheng AC, Chung G, Coats S, Eden PM, Hanestad K, Gallant PL, Gu Y, Huang X, Kendall RL, Lin MH, Morrison MJ, Patel VF, Radinsky R, Rose PE, Ross S, Sun JR, Tang J, Zhao H, Payton M, Geuns-Meyer SD. Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor. J Med Chem. 2010 Aug 4. PMID:20684549 doi:10.1021/jm100394y

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