2xns

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'''Unreleased structure'''
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[[Image:2xns.jpg|left|200px]]
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The entry 2xns is ON HOLD until Paper Publication
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{{STRUCTURE_2xns| PDB=2xns | SCENE= }}
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Authors: Bosch, D., Sammond, D.W., Butterfoss, G.L., Machius, M., Siderovski, D.P., Kuhlman, B.
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===CRYSTAL STRUCTURE OF HUMAN G ALPHA I1 BOUND TO A DESIGNED HELICAL PEPTIDE DERIVED FROM THE GOLOCO MOTIF OF RGS14===
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Description: Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:30:52 2010''
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{{ABSTRACT_PUBMED_21388199}}
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==About this Structure==
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[[2xns]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNS OCA].
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==Reference==
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<ref group="xtra">PMID:021388199</ref><ref group="xtra">PMID:017603074</ref><ref group="xtra">PMID:011976690</ref><references group="xtra"/>
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[[Category: Heterotrimeric G-protein GTPase]]
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[[Category: Homo sapiens]]
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[[Category: Bosch, D.]]
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[[Category: Butterfoss, G L.]]
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[[Category: Kuhlman, B.]]
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[[Category: Machius, M.]]
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[[Category: Sammond, D W.]]
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[[Category: Siderovski, D P.]]

Revision as of 05:09, 8 June 2011

Image:2xns.jpg

Template:STRUCTURE 2xns

CRYSTAL STRUCTURE OF HUMAN G ALPHA I1 BOUND TO A DESIGNED HELICAL PEPTIDE DERIVED FROM THE GOLOCO MOTIF OF RGS14

Template:ABSTRACT PUBMED 21388199

About this Structure

2xns is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sammond DW, Bosch DE, Butterfoss GL, Purbeck C, Machius M, Siderovski DP, Kuhlman B. Computational design of the sequence and structure of a protein-binding peptide. J Am Chem Soc. 2011 Mar 30;133(12):4190-2. Epub 2011 Mar 9. PMID:21388199 doi:10.1021/ja110296z
  • Sammond DW, Eletr ZM, Purbeck C, Kimple RJ, Siderovski DP, Kuhlman B. Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. J Mol Biol. 2007 Aug 31;371(5):1392-404. Epub 2007 Jun 8. PMID:17603074 doi:10.1016/j.jmb.2007.05.096
  • Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature. 2002 Apr 25;416(6883):878-81. PMID:11976690 doi:http://dx.doi.org/10.1038/416878a

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