3n7o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3n7o.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_3n7o", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_3n7o| PDB=3n7o | SCENE= }}
{{STRUCTURE_3n7o| PDB=3n7o | SCENE= }}
- 
===X-ray structure of human chymase in complex with small molecule inhibitor.===
===X-ray structure of human chymase in complex with small molecule inhibitor.===
 +
{{ABSTRACT_PUBMED_20599788}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN]] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
-
The line below this paragraph, {{ABSTRACT_PUBMED_20599788}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 20599788 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_20599788}}
+
==About this Structure==
==About this Structure==
-
3N7O is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7O OCA].
+
[[3n7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7O OCA].
==Reference==
==Reference==
-
<ref group="xtra">PMID:20599788</ref><references group="xtra"/>
+
<ref group="xtra">PMID:020599788</ref><references group="xtra"/><references/>
[[Category: Chymase]]
[[Category: Chymase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 37: Line 24:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Serine protease]]
[[Category: Serine protease]]
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:24:47 2010''
 

Revision as of 21:15, 17 April 2013

Template:STRUCTURE 3n7o

Contents

X-ray structure of human chymase in complex with small molecule inhibitor.

Template:ABSTRACT PUBMED 20599788

Function

[CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.

About this Structure

3n7o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kervinen J, Crysler C, Bayoumy S, Abad MC, Spurlino J, Deckman I, Greco MN, Maryanoff BE, de Garavilla L. Potency variation of small-molecule chymase inhibitors across species. Biochem Pharmacol. 2010 Oct 1;80(7):1033-41. Epub 2010 Jun 23. PMID:20599788 doi:10.1016/j.bcp.2010.06.014

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools