3o2a

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Revision as of 04:35, 29 September 2010

Image:3o2a.png

Template:STRUCTURE 3o2a

Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator

Template:ABSTRACT PUBMED 20805031

About this Structure

3O2A is a 1 chain structure with sequence from Rattus norvegicus, rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Jamieson C, Basten S, Campbell RA, Cumming IA, Gillen KJ, Gillespie J, Kazemier B, Kiczun M, Lamont Y, Lyons AJ, Maclean JK, Moir EM, Morrow JA, Papakosta M, Rankovic Z, Smith L. A novel series of positive modulators of the AMPA receptor: Discovery and structure based hit-to-lead studies. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5753-6. Epub 2010 Aug 13. PMID:20805031 doi:10.1016/j.bmcl.2010.07.138

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OCA

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