2vh6
From Proteopedia
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{{STRUCTURE_2vh6| PDB=2vh6 | SCENE= }} | {{STRUCTURE_2vh6| PDB=2vh6 | SCENE= }} | ||
===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH BIARYL P4 MOTIFS=== | ===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH BIARYL P4 MOTIFS=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2vh6]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VH6 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor Xa|Factor Xa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018054228</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Young, R J.]] | [[Category: Young, R J.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
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[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 04:18, 26 July 2012
Contents |
STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH BIARYL P4 MOTIFS
Template:ABSTRACT PUBMED 18054228
About this Structure
2vh6 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Chung CW, Convery MA, Kelly HA, Paul King N, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE. Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs. Bioorg Med Chem Lett. 2008 Jan 1;18(1):23-7. Epub 2007 Nov 17. PMID:18054228 doi:S0960-894X(07)01330-3
Categories: Coagulation factor Xa | Homo sapiens | Borthwick, A D. | Brown, D. | Burns-Kurtis, C L. | Campbell, M. | Chan, C. | Charbaut, M. | Chung, C W. | Convery, M A. | Kelly, H A. | King, N P. | Kleanthous, S. | Mason, A M. | Pateman, A J. | Patikis, A N. | Pinto, I L. | Pollard, D R. | Senger, S. | Shah, G P. | Toomey, J R. | Watson, N S. | Weston, H E. | Young, R J. | Blood coagulation | Cleavage on pair of basic residue | Complex | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Protease | Serine protease | Zymogen
