3nit
From Proteopedia
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{{STRUCTURE_3nit| PDB=3nit | SCENE= }} | {{STRUCTURE_3nit| PDB=3nit | SCENE= }} | ||
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===The structure of UBR box (native1)=== | ===The structure of UBR box (native1)=== | ||
| + | {{ABSTRACT_PUBMED_20835240}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/UBR1_YEAST UBR1_YEAST]] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | ||
| - | + | ==About this Structure== | |
| - | + | [[3nit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIT OCA]. | |
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| - | == | + | ==See Also== |
| - | + | *[[Ubiquitin protein ligase|Ubiquitin protein ligase]] | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020835240</ref><references group="xtra"/><references/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Choi, W S.]] | [[Category: Choi, W S.]] | ||
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[[Category: Ubr box]] | [[Category: Ubr box]] | ||
[[Category: Zinc-binding protein]] | [[Category: Zinc-binding protein]] | ||
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Revision as of 11:47, 24 April 2013
Contents |
The structure of UBR box (native1)
Template:ABSTRACT PUBMED 20835240
Function
[UBR1_YEAST] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
About this Structure
3nit is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Choi WS, Jeong BC, Joo YJ, Lee MR, Kim J, Eck MJ, Song HK. Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases. Nat Struct Mol Biol. 2010 Sep 12. PMID:20835240 doi:10.1038/nsmb.1907
