3oy3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3oy3 is ON HOLD Authors: Zhou, T., Commodore, L., Huang, W.S., Wang, Y., Thomas, M., Keats, J., Xu, Q., Rivera, V., Shakespeare, W.C., Clackson, T.,...) |
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| + | [[Image:3oy3.jpg|left|200px]] | ||
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3oy3", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_3oy3| PDB=3oy3 | SCENE= }} | ||
| - | + | ===Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589=== | |
| - | Description: Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589 | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_21118377}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21118377 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21118377}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3OY3 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY3 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:21118377</ref><references group="xtra"/> | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Clackson, T.]] | ||
| + | [[Category: Commodore, L.]] | ||
| + | [[Category: Dalgarno, D C.]] | ||
| + | [[Category: Huang, W S.]] | ||
| + | [[Category: Keats, J.]] | ||
| + | [[Category: Rivera, V.]] | ||
| + | [[Category: Shakespeare, W C.]] | ||
| + | [[Category: Thomas, M.]] | ||
| + | [[Category: Wang, Y.]] | ||
| + | [[Category: Xu, Q.]] | ||
| + | [[Category: Zhou, T.]] | ||
| + | [[Category: Zhu, X.]] | ||
| + | [[Category: Atp binding]] | ||
| + | [[Category: Phosphorylation]] | ||
| + | [[Category: Phosphotransferase]] | ||
| + | [[Category: Protein kinase two-domain fold]] | ||
| + | [[Category: Protein-inhibitor complex]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:44:23 2010'' | ||
Revision as of 05:32, 15 December 2010
Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589
Template:ABSTRACT PUBMED 21118377
About this Structure
3OY3 is a 2 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Zhou T, Commodore L, Huang WS, Wang Y, Thomas M, Keats J, Xu Q, Rivera VM, Shakespeare WC, Clackson T, Dalgarno DC, Zhu X. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem Biol Drug Des. 2011 Jan;77(1):1-11. doi:, 10.1111/j.1747-0285.2010.01054.x. Epub 2010 Nov 30. PMID:21118377 doi:10.1111/j.1747-0285.2010.01054.x
Page seeded by OCA on Wed Dec 15 08:44:23 2010
Categories: Mus musculus | Non-specific protein-tyrosine kinase | Clackson, T. | Commodore, L. | Dalgarno, D C. | Huang, W S. | Keats, J. | Rivera, V. | Shakespeare, W C. | Thomas, M. | Wang, Y. | Xu, Q. | Zhou, T. | Zhu, X. | Atp binding | Phosphorylation | Phosphotransferase | Protein kinase two-domain fold | Protein-inhibitor complex | Transferase-transferase inhibitor complex
