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3nnz

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Revision as of 08:31, 27 October 2010

Image:3nnz.png

Template:STRUCTURE 3nnz

Structure of rat neuronal nitric oxide synthase heme domain complexed with 6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine

Template:ABSTRACT PUBMED 20833542

About this Structure

3NNZ is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Li H, Fang J, Roman LJ, Martasek P, Poulos TL, Silverman RB. Peripheral but crucial: A hydrophobic pocket (Tyr706, Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2010 Aug 26. PMID:20833542 doi:10.1016/j.bmcl.2010.08.096

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