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3mdt

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{{Seed}}
 
[[Image:3mdt.png|left|200px]]
[[Image:3mdt.png|left|200px]]
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==About this Structure==
==About this Structure==
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3MDT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDT OCA].
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[[3mdt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDT OCA].
==Reference==
==Reference==
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Voriconazole]]
[[Category: Voriconazole]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:11:08 2010''
 

Revision as of 20:28, 14 March 2011

Image:3mdt.png

Template:STRUCTURE 3mdt

Voriconazole complex of Cytochrome P450 46A1

Template:ABSTRACT PUBMED 20667828

About this Structure

3mdt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mast N, Charvet C, Pikuleva IA, Stout CD. Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J Biol Chem. 2010 Oct 8;285(41):31783-95. Epub 2010 Jul 28. PMID:20667828 doi:10.1074/jbc.M110.143313
  • Mast N, White MA, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9546-51. Epub 2008 Jul 9. PMID:18621681

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