3mdr
From Proteopedia
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[[Image:3mdr.png|left|200px]] | [[Image:3mdr.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3mdr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDR OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tranylcypromine]] | [[Category: Tranylcypromine]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:14:33 2010'' | ||
Revision as of 18:22, 14 March 2011
Tranylcypromine complex of Cytochrome P450 46A1
Template:ABSTRACT PUBMED 20667828
About this Structure
3mdr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Mast N, Charvet C, Pikuleva IA, Stout CD. Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J Biol Chem. 2010 Oct 8;285(41):31783-95. Epub 2010 Jul 28. PMID:20667828 doi:10.1074/jbc.M110.143313
- Mast N, White MA, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9546-51. Epub 2008 Jul 9. PMID:18621681
Categories: Cholesterol 24-hydroxylase | Homo sapiens | Charvet, C. | Mast, N. | Pikuleva, I. | Stout, C D. | Cholesterol metabolism | Cyp46a1 | Endoplasmic reticulum | Heme | Iron | Lipid metabolism | Membrane | Metabolic enzyme | Metal-binding | Microsome | Monooxygenase | Nadp | Oxidoreductase | P450 | P450 46a1 | Steroid metabolism | Transmembrane | Tranylcypromine
