Pharmaceutical Drug Targets and Diseases

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**Cancer
**Cancer
-
***[[Antizyme Inhibitor]]
+
*** See: [[Cancer]]
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***Caspases
+
-
****[[Molecular_Playground/Caspase-6|Caspase-6]]
+
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****[[Molecular_Playground/Caspase-7_Dynamics|Caspase-7 Dynamics]]
+
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****[[Molecular_Playground/Caspase-9_Regulation|Caspase-9 Regulation]]
+
-
***[[User:Greg_Black/Sandbox_1|Cisplatin Information]]
+
-
***[[Michael Purol Sandbox 1|Cyclin Dependent Kinase Inhibitor]]
+
-
***[[NADPH Cytochrome P450 Oxidoreductase|Cytochrome P450 Oxidoreductase]]
+
-
***[[6-deoxyerythronolide_B_synthase_%28DEBS%29|DEBS]]
+
-
***[[Dihydrofolate_reductase|Dihydrofolate Reductase, the Target of Methotrexate]]
+
-
***[[Farnesoid X Receptor]]
+
-
***Growth Factors & Receptors
+
-
****Epidermal Growth Factor
+
-
*****[[Epidermal Growth Factor]]
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-
*****[[Epidermal Growth Factor Receptor]]
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****[[Hepatocyte Growth Factor Receptor]]
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****[[Human Epidermal Growth Factor Receptor 2]]
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-
****Insulin-Like Growth Factor
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*****[[Insulin-Like Growth Factor-1]]
+
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*****[[Insulin-Like Growth Factor-1 Receptor]]
+
-
****Vascular Growth Factor
+
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*****[[Vascular Endothelial Growth Factor]]
+
-
*****[[Vascular Endothelial Growth Factor Receptor]]
+
-
***[[Molecular_Playground/FIH|Hypoxia Inducible Factor (HIF)]]
+
-
***[[User:Yash_Patankar/Sandbox_1|Heat Shock Protein 90]]
+
-
***[[1ebm|Human 8-Oxoguanine Glycosylase Structure and Mechanism (HOGG1)]]
+
-
***Kinases
+
-
****[[Cory_Tiedeman_sandbox|Cyclin Dependent Kinase-4]]
+
-
****[[Cell Division Cycle 7-Related Protein Kinase]]
+
-
****[[Mammalian Target of Rapamycin]]
+
-
****Mitogen-Activated Proteins
+
-
*****Mitogen-Activated Protein Kinase
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*****Mitogen-Activated Protein Kinase Kinase
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*****Mitogen-Activated Protein Kinase Kinase Kinase
+
-
******[[c-Raf]]
+
-
****[[Phosphatidylinositol 3-Kinase]]
+
-
****[[SRC]]
+
-
***[[P-glycoprotein:_Why_Cancer_Drugs_Fail|P-Glycoprotein: Why Cancer Drugs Fail]]
+
-
***Oncogenes
+
-
****[[C-Myc]] - Proto-Oncogenic Gene
+
-
****[[P53]] - Tumor Suppressing Gene
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-
****[[PTEN]]
+
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****[[Matt Routh sandbox|MDM2 Bound to p53]]
+
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****[[SRC]] - Proto-Oncogenic Tyrosine Kinase Gene
+
-
***[[Ann_Taylor_sandbox_Proteins_in_Cancer|Proteins in Cancer]]
+
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***[[Ras|Ras Superfamily]]
+
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***[[Chad Sorenson sandbox 1|Retinoblastoma Protein]]
+
-
***[[Molecular_Playground/Taxol|Taxol Information]]
+
-
***[[Telomerase Reverse Transcriptase]]
+
-
***[[User:Sarah Abdalla/Thioredoxin Reductase|Thioredoxin Reductase]]
+
-
***[[Molecular_Playground/TRAIL|Tumor-Necrosis Factor Apoptosis-Inducing Ligand]]
+
-
***[[Molecular_Playground/YKL-40|YKL-40]]
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**Compromised Immune System
**Compromised Immune System
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**Diabetes & Hypoglycemia
**Diabetes & Hypoglycemia
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***[[Molecular_Playground/Insulin|Insulin Information]]
+
*** [[See: Diabetes]]
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***[[Sandbox 67|Insulin Structure]]
+
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***[[User:Mary Ball/Leptin|Leptin]]
+
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***[[Peroxisome Proliferator-Activated Receptors]]
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***[[Molecular_Playground/YKL-40|YKL-40]]
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**Digestive Diseases
**Digestive Diseases
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**Metabolic Disorders
**Metabolic Disorders
-
***[[Acid-beta-glucosidase]]
+
** See: [[Metabolic Disorders]]
-
***[[Molecular_playground/beta_2_microglobulin|ß-2 Microglobulin]]
+
-
***[[HMG-CoA Reductase]]
+
-
***[[Molecular_Playground/Human_PPCA|Protective Protein/Cathepsin A (PPCA)]]
+
-
***[[Molecular_Playground/Human_Protective_Protein_Cathepsin_A|Protective Protein/Cathepsin A (PPCA) 2]]
+
-
***[[Bacterial thiolase|Thiolase]]
+
-
***[[Treatment_of_Gaucher_disease]]
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-
***[[Molecular_Playground/Velaglucerase|Velaglucerase]]
+
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***[[Disulfide Connectivity of Velaglucerase|Velaglucerase Disulfide Connectivity]]
+
**Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders
**Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders
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**Viral Infection
**Viral Infection
***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]]
***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]]
-
*** HIV
+
*** See: [[Human Immunodeficiency Virus]]
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****[[User:Eric Martz/Molecular Playground/HIVDrug|HIV-1 Drug]]
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****[[HIV-1 protease|HIV-1 Protease]]
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****[[User:Tsung-Yi_Lin/Sandbox|HIV-1 Protease Analysis]]
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****[[HIV-1 Gag]]
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****[[1gwp|HIV-1 Gag N-terminal Domain]]
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****[[HIV-1 Gag Recruitment of Tsg101 and the Viral Budding Process]]
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****[[HIV-1 NEF]]
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****[[Molecular_Playground/HIV_Protease_Inhibitor|HIV-1 Protease Inhibitor]]
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****[[HIV-1_Subtype_C_Protease|HIV-1 Subtype C Protease]]
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****[[Retroviral Integrase]]
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****[[Reverse Transcriptase]]
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****[[Tetherin]]
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*** Influenza
*** Influenza
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**** [[Avian Influenza Neuraminidase, Tamiflu and Relenza]]
+
*** See: [[Influenza]]
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**** [[Avian Influenza Neuraminidase, Tamiflu and Relenza]]
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**** H1N1 Sequence Analyses
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****** [[User:Michael_Strong/H1N1|H1N1 Swine Flu Sequence Analysis]]
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****** [[User:Michael_Strong/H1N1/MP1/MSA|H1N1 Swine Flu Multiple Sequence Alignment]]
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****** [[User:Michael Strong/H1N1/MP2/MSA|H1N1 Sequence Alignment of MP2 Protein]]
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****** [[User:Michael_Strong/H1N1/PB2|H1N1 Sequence Alignment of PB2 Protein]]
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****** [[User:Michael_Strong/H1N1/PB1|H1N1 Sequence Alignment of PB1 Protein]]
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****** [[User:Michael_Strong/H1N1/NS2/MSA|H1N1 Sequence Alignment of NS2 Protein]]
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****** [[User:Michael_Strong/H1N1/PA|H1N1 Sequence Alignment of PA Protein]]
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****** [[User:Michael_Strong/H1N1/HA|H1N1 Sequence Alignment of HA Protein]]
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-
****** [[User:Michael_Strong/H1N1/NP|H1N1 Sequence Alignment of NP Protein]]
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-
****** [[User:Michael_Strong/H1N1/NA|H1N1 Sequence Alignment of NA Protein]]
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****** [[User:Michael_Strong/H1N1/MP|H1N1 Sequence Alignment of MP Protein]]
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****** [[User:Michael_Strong/H1N1/NS|H1N1 Sequence Alignment of NS Protein]]
+
-
**** [[SAndbox_159|Hemagglutinins]]
+
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**** [[Influenza hemagglutinin]]
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**** [[Molecular_Playground/Influenza_A_M2_transmembrane_domain|Influenza A M2 Transmembrane Domain]]
+
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**** [[Proton Channels]] featuring a morph of the M2 proton channel of influenza.
+
-
**** [[Molecular Playground/Tamiflu|Tamiflu]]
+
-
**** [[Molecular Playground/Relenza|Relenza]]
+
*** [[Herpes Simplex Virus Thymidine Kinase]]
*** [[Herpes Simplex Virus Thymidine Kinase]]
*** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]]
*** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]]
}}
}}

Revision as of 16:47, 13 October 2010

AstraZeneca’s Nexium
AstraZeneca’s Nexium

The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease.

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