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Fasciculin
From Proteopedia
(New page: Crystal Structure of Fasciculin 1fas {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE= |right|CAPTION=Fasciculin 1fas }}) |
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[[Image:1fas.png|left|200px|thumb|Crystal Structure of Fasciculin [[1fas]]]] | [[Image:1fas.png|left|200px|thumb|Crystal Structure of Fasciculin [[1fas]]]] | ||
| - | {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE= |right|CAPTION=Fasciculin [[1fas]] }} | + | {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} |
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| + | [[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). | ||
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| + | {{TOC limit|limit=2}} | ||
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| + | == 3D Structures of Fasciculin == | ||
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| + | === Fasciculin === | ||
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| + | [[1fas]] – FASI <br /> | ||
| + | [[1fsc]] - FASII<br /> | ||
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| + | === FAS+ AChE === | ||
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| + | [[2x8b]], [[1b41]] – FASII+hAChE – human<br /> | ||
| + | [[1f8u]] - FASII+hAChE (mutant)<br /> | ||
| + | [[1ku6]], [[1mah]] - FASII+mAChE – mouse<br /> | ||
| + | [[1fss]] - FASII+AChE – ''Torpedo californica''<br /> | ||
Revision as of 10:03, 24 October 2010
Fasciculins (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas).
3D Structures of Fasciculin
Fasciculin
FAS+ AChE
2x8b, 1b41 – FASII+hAChE – human
1f8u - FASII+hAChE (mutant)
1ku6, 1mah - FASII+mAChE – mouse
1fss - FASII+AChE – Torpedo californica
