3mwv

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Revision as of 07:46, 1 December 2010

Template:STRUCTURE 3mwv

Crystal structure of HCV NS5B polymerase

Template:ABSTRACT PUBMED 20942454

About this Structure

3MWV is a 2 chains structure with sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Laplante SR, Gillard JR, Jakalian A, Aubry N, Coulombe R, Brochu C, Tsantrizos YS, Poirier M, Kukolj G, Beaulieu PL. Importance of Ligand Bioactive Conformation in the Discovery of Potent Indole-Diamide Inhibitors of the Hepatitis C Virus NS5B. J Am Chem Soc. 2010 Oct 13. PMID:20942454 doi:10.1021/ja101358s

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