3otq

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[[Category: Hydrolase]]
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Revision as of 08:12, 3 November 2010

Image:3otq.png

Template:STRUCTURE 3otq

Soluble Epoxide Hydrolase in complex with pyrazole antagonist

Template:ABSTRACT PUBMED 20934334

About this Structure

3OTQ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lo HY, Man CC, Fleck RW, Farrow NA, Ingraham RH, Kukulka A, Proudfoot JR, Betageri R, Kirrane T, Patel U, Sharma R, Hoermann MA, Kabcenell A, Lombaert SD. Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6379-83. Epub 2010 Sep 19. PMID:20934334 doi:10.1016/j.bmcl.2010.09.095

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