3m45

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[[Image:3m45.png|left|200px]]
 
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{{STRUCTURE_3m45| PDB=3m45 | SCENE= }}
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===Crystal structure of Ig1 domain of mouse SynCAM 2===
===Crystal structure of Ig1 domain of mouse SynCAM 2===
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{{ABSTRACT_PUBMED_20739279}}
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==Function==
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[[http://www.uniprot.org/uniprot/CADM2_MOUSE CADM2_MOUSE]] Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (By similarity).
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(as it appears on PubMed at http://www.pubmed.gov), where 20739279 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20739279}}
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==About this Structure==
==About this Structure==
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3M45 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M45 OCA].
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[[3m45]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M45 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20739279</ref><references group="xtra"/>
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<ref group="xtra">PMID:020739279</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Modis, Y.]]
[[Category: Modis, Y.]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:22:36 2010''
 

Revision as of 23:25, 10 April 2013

Template:STRUCTURE 3m45

Contents

Crystal structure of Ig1 domain of mouse SynCAM 2

Template:ABSTRACT PUBMED 20739279

Function

[CADM2_MOUSE] Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (By similarity).

About this Structure

3m45 is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T. N-glycosylation at the SynCAM immunoglobulin interface modulates synaptic adhesion. J Biol Chem. 2010 Aug 25. PMID:20739279 doi:10.1074/jbc.M110.120865

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