3oj8

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'''Unreleased structure'''
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[[Image:3oj8.jpg|left|200px]]
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The entry 3oj8 is ON HOLD until Paper Publication
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{{STRUCTURE_3oj8| PDB=3oj8 | SCENE= }}
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Authors: Mileni, M., Stevens, R.C., Boger, D.L.
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===Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain===
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Description: Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:31:51 2010''
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{{ABSTRACT_PUBMED_21428410}}
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==About this Structure==
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[[3oj8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OJ8 OCA].
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==Reference==
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<ref group="xtra">PMID:021428410</ref><references group="xtra"/>
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[[Category: Fatty acid amide hydrolase]]
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[[Category: Rattus norvegicus]]
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[[Category: Boger, D L.]]
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[[Category: Mileni, M.]]
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[[Category: Stevens, R C.]]
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[[Category: Enantiomer]]
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[[Category: Faah]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Membrane]]
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[[Category: Oxazole]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Serine hydrolase]]

Revision as of 18:51, 6 July 2011

Image:3oj8.jpg

Template:STRUCTURE 3oj8

Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain

Template:ABSTRACT PUBMED 21428410

About this Structure

3oj8 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. Reversible competitive alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. J Med Chem. 2011 Apr 28;54(8):2805-22. Epub 2011 Mar 23. PMID:21428410 doi:10.1021/jm101597x

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