This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3pi5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 3pi5 is ON HOLD until Paper Publication Authors: Rondeau, J.M. Description: Crystal Structure of Human Beta Secretase in Complex with BFG356 ''Pag...)
Line 1: Line 1:
-
'''Unreleased structure'''
+
[[Image:3pi5.jpg|left|200px]]
-
The entry 3pi5 is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3pi5", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3pi5| PDB=3pi5 | SCENE= }}
-
Authors: Rondeau, J.M.
+
===Crystal Structure of Human Beta Secretase in Complex with BFG356===
-
Description: Crystal Structure of Human Beta Secretase in Complex with BFG356
 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:34:31 2010''
+
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_21388807}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 21388807 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_21388807}}
 +
 
 +
==About this Structure==
 +
[[3pi5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PI5 OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:21388807</ref><ref group="xtra">PMID:19195886</ref><ref group="xtra">PMID:19195887</ref><references group="xtra"/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Memapsin 2]]
 +
[[Category: Rondeau, J M.]]

Revision as of 07:03, 23 March 2011

Image:3pi5.jpg

Template:STRUCTURE 3pi5

Crystal Structure of Human Beta Secretase in Complex with BFG356

Template:ABSTRACT PUBMED 21388807

About this Structure

3pi5 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rueeger H, Rondeau JM, McCarthy C, Mobitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. Epub 2011 Feb 15. PMID:21388807 doi:10.1016/j.bmcl.2011.02.038
  • Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P. Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. Epub 2009 Jan 19. PMID:19195886 doi:10.1016/j.bmcl.2009.01.036
  • Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3pi5"
Personal tools