This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Leucine-rich repeat

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m
m
Line 13: Line 13:
Articles in Proteopedia concerning Leucine-rich repeat proteins include:
Articles in Proteopedia concerning Leucine-rich repeat proteins include:
- 
**[[1xvd|Human Follicle Stimulating Hormone Complexed with its Receptor]]
**[[1xvd|Human Follicle Stimulating Hormone Complexed with its Receptor]]
**[[Variable Lymphocyte Receptors]]
**[[Variable Lymphocyte Receptors]]
Line 21: Line 20:
{{STRUCTURE_1xwd| PDB=1xwd | SCENE= }}
{{STRUCTURE_1xwd| PDB=1xwd | SCENE= }}
To view automatically seeded indices concerning Leucine-rich repeat proteins, see:
To view automatically seeded indices concerning Leucine-rich repeat proteins, see:
-
**[[:Category:Leucine-rich repeat|Leucine-rich repeat]]
+
*[[:Category:Leucine-rich repeat|Leucine-rich repeat]]
-
**[[:Category:Leucine-rich-repeat|Leucine-rich-repeat]]
+
*[[:Category:Leucine-rich-repeat|Leucine-rich-repeat]]
-
**[[:Category:Leucine-rich repeat-containing protein 4|Leucine-rich repeat-containing protein 4]]
+
*[[:Category:Leucine-rich repeat-containing protein 4|Leucine-rich repeat-containing protein 4]]
-
**[[:Category:Lrr|LRR]]
+
*[[:Category:Lrr|LRR]]
-
**[[:Category:Leucine-rich repeat glycoprotein|Leucine-rich repeat glycoprotein]]
+
*[[:Category:Leucine-rich repeat glycoprotein|Leucine-rich repeat glycoprotein]]
==References==
==References==

Revision as of 03:06, 19 November 2010

A large family of over 60,000 proteins feature horseshoe- or arc-shaped domains made of leucine-rich repeats, which are named for a repeated motif that always contains leucine.[1]

PDB ID 3e6j

Drag the structure with the mouse to rotate
Lamprey Variable Lymphocyte Receptor (3e6j), resolution 1.67Å ()
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Articles in Proteopedia concerning Leucine-rich repeat proteins include:



PDB ID 1xwd

Drag the structure with the mouse to rotate
1xwd, resolution 2.92Å ()
Ligands: , ,
Gene: CGA (Homo sapiens), FSHB (Homo sapiens), FSHR (Homo sapiens)
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


To view automatically seeded indices concerning Leucine-rich repeat proteins, see:

References

  1. ↑ Matsushima N, Miyashita H, Mikami T, Kuroki Y. A nested leucine rich repeat (LRR) domain: the precursor of LRRs is a ten or eleven residue motif. BMC Microbiol. 2010 Sep 9;10:235. PMID:20825685 doi:10.1186/1471-2180-10-235

See Also

Additional Literature

  • Kobe B, Kajava AV. The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol. 2001 Dec;11(6):725-32. PMID:11751054
  • Matsushima N, Tanaka T, Enkhbayar P, Mikami T, Taga M, Yamada K, Kuroki Y. Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors. BMC Genomics. 2007 May 21;8:124. PMID:17517123 doi:10.1186/1471-2164-8-124
  • Matsushima N, Tachi N, Kuroki Y, Enkhbayar P, Osaki M, Kamiya M, Kretsinger RH. Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases. Cell Mol Life Sci. 2005 Dec;62(23):2771-91. PMID:16231091 doi:10.1007/s00018-005-5187-z
  • Kajava AV, Kobe B. Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information. Protein Sci. 2002 May;11(5):1082-90. PMID:11967365 doi:10.1110/ps.4010102

Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Jaime Prilusky, Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Leucine-rich_repeat"
Personal tools