Sandbox c12
From Proteopedia
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<scene name='Sandbox_c12/Label/1'>Tacrines ring</scene> is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (<scene name='Sandbox_c12/Residuos_84_y_330/1'>W84 and F330</scene>)<ref>pmid 8415649</ref> | <scene name='Sandbox_c12/Label/1'>Tacrines ring</scene> is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (<scene name='Sandbox_c12/Residuos_84_y_330/1'>W84 and F330</scene>)<ref>pmid 8415649</ref> | ||
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Revision as of 13:30, 23 November 2010
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1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine.
Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor.
It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 ()[1]
