Sandbox c20
From Proteopedia
| Line 9: | Line 9: | ||
Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | ||
| - | + | [[On October 7th, 2009 the Nobel Committee announced three structural biologists would share the 2009 Nobel Prize in Chemistry for studies of the The Ribosome]] | |
<scene name='Sandbox_c20/Sitios_de_union_de_tartrina/1'>W84 and F330</scene> | <scene name='Sandbox_c20/Sitios_de_union_de_tartrina/1'>W84 and F330</scene> | ||
| Line 15: | Line 15: | ||
<ref>PMID 8415649</ref> | <ref>PMID 8415649</ref> | ||
<references/> | <references/> | ||
| - | [[This is the time when blood comes into action. Blood is a specialized body fluid that delivers necessary substances to the body's cells – such as nutrients and oxygen – and transports waste products away from those same cells. Because oxygen is not very soluble in blood, animals have an efficient mechanism for capturing oxygen, transporting, and releasing it by the inner cells: hemoglobin.]] | ||
Revision as of 13:41, 23 November 2010
hola como estas? bien y vos?
|
1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine.
Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor.
It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). On October 7th, 2009 the Nobel Committee announced three structural biologists would share the 2009 Nobel Prize in Chemistry for studies of the The Ribosome
Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site go [1]
