Beta secretase
From Proteopedia
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'''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''', is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention. | '''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''', is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention. | ||
Revision as of 04:41, 30 November 2010
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β-Secretase, also known as BACE (β-site of Amyloid precursor protein Cleaving Enzyme) and Memapsin 2, is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention.
Contents |
Structure of Beta Secretase
Important Structures
Alzheimer's Disease
Inhibition of Beta Secretase
References
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Daniel Santos, Jaime Prilusky, Joel L. Sussman, David Canner
