3krj
From Proteopedia
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| - | + | [[Image:3krj.png|left|200px]] | |
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===cFMS tyrosine kinase in complex with 4-Cyano-1H-imidazole-2-carboxylic acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide=== | ===cFMS tyrosine kinase in complex with 4-Cyano-1H-imidazole-2-carboxylic acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22039836}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22039836 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22039836}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3krj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRJ OCA]. | |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022039836</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:30:23 2010'' | ||
Revision as of 10:47, 14 December 2011
cFMS tyrosine kinase in complex with 4-Cyano-1H-imidazole-2-carboxylic acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide
Template:ABSTRACT PUBMED 22039836
About this Structure
3krj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Illig CR, Manthey CL, Wall MJ, Meegalla SK, Chen J, Wilson KJ, Ballentine SK, Desjarlais RL, Schubert C, Crysler CS, Chen Y, Molloy CJ, Chaikin MA, Donatelli RR, Yurkow E, Zhou Z, Player MR, Tomczuk BE. Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidiny l]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). J Med Chem. 2011 Nov 24;54(22):7860-83. Epub 2011 Oct 31. PMID:22039836 doi:10.1021/jm200900q
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Schubert, C. | Atp-binding | Chimera | Disulfide bond | Glycoprotein | Immunoglobulin domain | Inhibitor | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Receptor | Transferase | Transferase-transferase inhibitor complex | Transmembrane | Tyrosine-protein kinase
