HIV Protease Inhibitor Resistance Profile

From Proteopedia

(Difference between revisions)

Revision as of 11:57, 2 December 2010

This page serves as a hub for visualizing various Ligands, Cofactors and Coenzymes. Click on the green links below for a 3D rendering of the compound, or follow the links below to pages with additional information about the compound and a list of proteins that bind it.


Inhibitor/ Mutation Site	L10	V11	I13	G16	K20	L24	D30	V32	L33	E34	E35	M36	K43	M46	I47	G48	I50	F53	I54	Q58	D60	I62	L63	I64	H69	A71	G73	T74	L76	V77	V82	N83	I84	I85	N88	L89	L90	I93
Ritonavir	I,R,V	-	-	-	M,R	-	-	I	F	-	-	I	-	I,L	-	-	-	-	V,L	-	-	-	-	-	-	V,T	-	-	-	I	A,F,T, S	-	V	-	-	-	M	-
Indinavir	I,R,V	-	-	-	M,R	I	-	I	-	-	-	I	-	I,L	-	-	-	-	V	-	-	-	-	-	-	V,T	S,A	-	-	I	A,F,T		V	-	-	-	M	-
Saquinavir	I,R,V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	-	-	V,L	-	-	-	-	-	-	V,T	S	-	-	I	A	-	V	-	-	-	M	-
Nelfinavir	F,I	-	-	-	-	-	N	-	-	-	-	I	-	I,L	-	-	-	-	-	-	-	-	-	-	-	V,T	-	-	-	I	A,F,T, S	-	V	-	D,S		M	-
Amprenavir	F,I,R, V	-	-	-	-	-	-	I	-	-	-	-	-	I,L	V	-	V	-	L,V,M	-	-	-	-	-	-	-	S	-	-	-	-	-	V	-	-	-	M	-
Atazanavir	I,F,V	-	-	-	R,M,I	I	-	I	I,F,V	-	-	I,L,V	-	I	-	V	L	-	L	-	-	-	-	-	-	V	C,S,T, A	-	-	-	A	-	V	-	S	-	M	-
Lopinavir & Ritonavir	F,I,R, V	-	-	-	M,R	I	-	I	F	-	-	-	-	I,L	V,A	-	V	L	V,L,A, M,T,S	-	-	-	P	-	-	V,T	S	-	V	-	A,F,T, S	-	V	-	-	-	M
Atazanavir & Ritonavir	I,F,V, C	-	-	E	R,M,I, T,V	I	-	I	I,F,V	Q	-	I,L,V	-	I,L	-	V	V	L,Y	L,V,M, T,A	-	E	V	-	L,M,V	-	V,I,T, L	C,S,T, A	-	-	-	A,T,F, I	-	V	V	S	-	M	L,M
Darunavir & Ritonavir	-	I	-	-	-	-	-	I	F	-	-	-	-	-	V	-	V	-	M,L	-	-	-	-	-	-	-	-	P	V	-	-	-	V	-	-	V	-	-
Fosamprenavir & Ritonavir	F,I,R, V	-	-	-	-	-	-	I	-	-	-	-	-	I,L	V	-	V	-	L,V,M	-	-	-	-	-	-	-	S	-	V	-	A,F,S, T	-	V	-	-	-	M	-
Indinavir & Ritonavir	I,R,V	-	-	-	M,R	I	-	I	-	-	-	I	-	I,L	-	-	-	-	V	-	-	-	-	-	-	V,T	S,A	-	V	I	A,F,T	-	V	-	-	-	M	-
Saquinavir & Ritonavir	I,R,V	-	-	-	-	I	-	-	-	-	-	-	-	-	-	V	-	-	V,L	-	-	V	-	-	-	V,T	S	-	-	I	A,F,T, S	-	V	-	-	-	M	-
Tipranavir & Ritonavir	V	-	V	-	M,R	-	-	-	F	-	G	I	T	L	V	-	-	-	A,M,V	E	-	-	-	-	K	-	-	P	-	-	L,T	D	V	-	-	-	M	-

Proteopedia Page Contributors and Editors (what is this?)

David Canner

Retrieved from "http://52.214.119.220/wiki/index.php/HIV_Protease_Inhibitor_Resistance_Profile"

HIV Protease Inhibitor Resistance Profile

From Proteopedia

Revision as of 11:57, 2 December 2010

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox

@@ Line 18: / Line 18: @@
 </tr>
 </table>
-{| class="wikitable" border="1" width="95%" style="text-align:center"
-|-
-!  colspan="37" align="center"| Resistance Mutations <ref>PMID:17646201</ref><ref>PMID: 20068260</ref><ref>PMID: 14724329</ref>
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|-
-! Inhibitor/Mutation Site
-!L10
-!I13
-!G16
-!K20
-!L24
-!D30
-!V32
-!L33
-!E34
-!E35
-!M36
-!K43
-!M46
-!I47
-!G48
-!I50
-!F53
-!I54
-!D60
-!I62
-!L63
-!I64
-!H69
-!A71
-!G73
-!T74
-!L76
-!V77
-!V82
-!N83
-!I84
-!I85
-!N88
-!L89
-!L90
-!I93
-|}