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HIV Protease Resistance

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Revision as of 13:16, 2 December 2010

Resistance Mutations
Visualize Inhibitor/Mutation Site L10 V11 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Ritonavir I,R,V - - - M,R - - I F - - I - I,L - - - - V,L QQQ - - - - - V,T - - - I A,F,T,S - V - - - M -
Indinavir I,R,V - - - M,R I - I - - - I - I,L - - - - V - - - - - V,T S,A - - I A,F,T V - - - M -
Visualize Saquinavir I,R,V - - - - - - - - - - - - - - V - - V,L QQQ - - - - - V,T S - - I A - V - - - M -
Visualize Nelfinavir F,I - - - - - N - - - - I - I,L QQQ - - - - - - - - - - V,T - - - I A,F,T,S - V - D,S M -
Visualize Amprenavir F,I,R,V - - - - - - I - - - - - I,L V - V - L,V,M QQQ - - - - - - S - - - - - V - - - M -
Visualize Atazanavir I,F,V - - - R,M,I I - I I,F,V - - I,L,V - I - V L QQQ - L - - - - - V C,S,T,A - - - A - V - S - M -
Visualize Lopinavir & Ritonavir F,I,R,V - - - M,R I - I F - - - - I,L V,A - V L V,L,A,M,T,S - - P - - V,T S - V - A,F,T,S - V - - - M
Visualize Atazanavir & Ritonavir I,F,V,C - - E R,M,I,T,V I - I I,F,V Q - I,L,V - I,L QQQ - V V L,Y L,V,M,T,A E V - L,M,V - V,I,T,L C,S,T,A - - - A,T,F,I - V V S - M L,M
Visualize Darunavir & Ritonavir - I - - - - - I F - - - - - V - V - M,L QQQ - - - - - - - P V - - - V - - V - -
Visualize Fosamprenavir & Ritonavir F,I,R,V - - - - - - I - - - - - I,L V - V - L,V,M QQQ - - - - - - S - V - A,F,S,T - V - - - M -
Visualize Indinavir & Ritonavir I,R,V - - - M,R I - I - - - I - I,L QQQ - - - - V - - - - - V,T S,A - V I A,F,T - V - - - M -
Visualize Saquinavir & Ritonavir I,R,V - - - - I - - - - - - - - - V - - V,L QQQ - V - - - V,T S - - I A,F,T,S - V - - - M -
Visualize Tipranavir & Ritonavir V - V - M,R - - - F - G I T L V QQQ - - - A,M,V E - - - - K - - P - - L,T D V - - - M -

Proteopedia Page Contributors and Editors (what is this?)

David Canner

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