Tol
From Proteopedia
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| - | The Tol system, also known as Tol-Pal, is a multiprotein complex in the cell envelope of many Gram-negative bacteria. It contains 7 proteins organised in two operons. | + | The Tol system, also known as Tol-Pal, is a multiprotein complex in the cell envelope of many Gram-negative bacteria. It contains 7 proteins ([[TolQ]], [[TolR]], [[TolA]], [[TolB]], [[Pal]], [[YbgF]], [[YbgC]]) organised in two operons. |
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==Structure== | ==Structure== | ||
Revision as of 16:30, 3 December 2010
The Tol system, also known as Tol-Pal, is a multiprotein complex in the cell envelope of many Gram-negative bacteria. It contains 7 proteins (TolQ, TolR, TolA, TolB, Pal, YbgF, YbgC) organised in two operons.
Contents |
Structure
Function
Regulation
It has been shown that the regulation of Tol genes is linked to the cell envelope stability. [1] In studies with E. coli, the tol-pal genes have been induced by RcsC in response to cell envelope stress. [2] RcsC is a transmembrane sensor kinase, and along with the cytoplasmic response regulator RcsB, makes up the RcsBC regulatory system. [3] RcsBC is involved in the regulation of cps genes which code for the biosynthsis machinery of a major componant for the capsula, cholanic acid.
