3ovz

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ovz.jpg|left|200px]]
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The entry 3ovz is ON HOLD
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{{STRUCTURE_3ovz| PDB=3ovz | SCENE= }}
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Authors: Fradera, X., van Zeeland, M., Uitdehaag, J.C.M.
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===Cathepsin K in complex with a covalent inhibitor with a ketoamide warhead===
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Description: Cathepsin K in complex with a covalent inhibitor with a ketoamide warhead
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:22:26 2010''
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{{ABSTRACT_PUBMED_21030256}}
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==About this Structure==
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3OVZ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVZ OCA].
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==Reference==
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<ref group="xtra">PMID:21030256</ref><references group="xtra"/>
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[[Category: Cathepsin K]]
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[[Category: Homo sapiens]]
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[[Category: Fradera, X.]]
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[[Category: Uitdehaag, J C.M.]]
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[[Category: Zeeland, M van.]]
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[[Category: Cathepsin k]]
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[[Category: Covalent inhibitor]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Ketoamide warhead]]
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[[Category: Ligand forms covalent bond to cys25]]
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[[Category: Lysosome]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:57:57 2010''

Revision as of 06:45, 22 December 2010

Template:STRUCTURE 3ovz

Cathepsin K in complex with a covalent inhibitor with a ketoamide warhead

Template:ABSTRACT PUBMED 21030256

About this Structure

3OVZ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cai J, Robinson J, Belshaw S, Everett K, Fradera X, van Zeeland M, van Berkom L, van Rijnsbergen P, Popplestone L, Baugh M, Dempster M, Bruin J, Hamilton W, Kinghorn E, Westwood P, Kerr J, Rankovic Z, Arbuckle W, Bennett DJ, Jones PS, Long C, Martin I, Uitdehaag JC, Meulemans T. Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6890-4. Epub 2010 Oct 26. PMID:21030256 doi:10.1016/j.bmcl.2010.10.012

Page seeded by OCA on Wed Dec 22 09:57:57 2010

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