3lok
From Proteopedia
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{{STRUCTURE_3lok| PDB=3lok | SCENE= }} | {{STRUCTURE_3lok| PDB=3lok | SCENE= }} | ||
===Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393=== | ===Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393=== | ||
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{{ABSTRACT_PUBMED_21080395}} | {{ABSTRACT_PUBMED_21080395}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3lok]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOK OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021080395</ref><references group="xtra"/> |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:53:27 2010'' | ||
Revision as of 03:26, 27 July 2012
Contents |
Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393
Template:ABSTRACT PUBMED 21080395
About this Structure
3lok is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Kluter S, Simard JR, Rode HB, Grutter C, Pawar V, Raaijmakers HC, Barf TA, Rabiller M, van Otterlo WA, Rauh D. Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance. Chembiochem. 2010 Dec 10;11(18):2557-66. PMID:21080395 doi:10.1002/cbic.201000352
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Gruetter, C. | Rauh, D. | Rode, H B. | Atp-binding | Covalent inhibitor | Drug resistance | Irreversible inhibitor | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Pd168393 | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | Src kinase domain | Transferase-transferase inhibitor complex | Tyrosine-protein kinase
