3opt

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{{STRUCTURE_3opt| PDB=3opt | SCENE= }}
{{STRUCTURE_3opt| PDB=3opt | SCENE= }}
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===Crystal structure of the Rph1 catalytic core with a-ketoglutarate===
===Crystal structure of the Rph1 catalytic core with a-ketoglutarate===
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{{ABSTRACT_PUBMED_21067515}}
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==Function==
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[[http://www.uniprot.org/uniprot/RPH1_YEAST RPH1_YEAST]] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.<ref>PMID:10523651</ref> <ref>PMID:11809875</ref>
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{{ABSTRACT_PUBMED_21067515}}
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==About this Structure==
==About this Structure==
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3OPT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA].
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[[3opt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:21067515</ref><references group="xtra"/>
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<ref group="xtra">PMID:021067515</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chang, Y.]]
[[Category: Chang, Y.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Rph1]]
[[Category: Rph1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:57:29 2010''
 

Revision as of 08:12, 2 May 2013

Template:STRUCTURE 3opt

Contents

Crystal structure of the Rph1 catalytic core with a-ketoglutarate

Template:ABSTRACT PUBMED 21067515

Function

[RPH1_YEAST] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.[1] [2]

About this Structure

3opt is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Chang Y, Wu J, Tong XJ, Zhou JQ, Ding J. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism. Biochem J. 2010 Nov 10. PMID:21067515 doi:10.1042/BJ20101418
  1. ↑ Jang YK, Wang L, Sancar GB. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol. 1999 Nov;19(11):7630-8. PMID:10523651
  2. ↑ Kim EM, Jang YK, Park SD. Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res. 2002 Feb 1;30(3):643-8. PMID:11809875

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