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2hu6
From Proteopedia
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[[Image:2hu6.png|left|200px]] | [[Image:2hu6.png|left|200px]] | ||
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{{STRUCTURE_2hu6| PDB=2hu6 | SCENE= }} | {{STRUCTURE_2hu6| PDB=2hu6 | SCENE= }} | ||
===Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor=== | ===Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor=== | ||
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{{ABSTRACT_PUBMED_16899369}} | {{ABSTRACT_PUBMED_16899369}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2hu6]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HU6 OCA]. | + | [[2hu6]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HU6 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Elastase]] | + | *[[Elastase|Elastase]] |
| + | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016899369</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
Revision as of 06:41, 26 July 2012
Contents |
Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor
Template:ABSTRACT PUBMED 16899369
About this Structure
2hu6 is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mannino C, Nievo M, Machetti F, Papakyriakou A, Calderone V, Fragai M, Guarna A. Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg Med Chem. 2006 Nov 15;14(22):7392-403. Epub 2006 Aug 8. PMID:16899369 doi:10.1016/j.bmc.2006.07.028
