3b7o
From Proteopedia
(New page: 200px<br /><applet load="3b7o" size="350" color="white" frame="true" align="right" spinBox="true" caption="3b7o, resolution 1.60Å" /> '''Crystal structure of...) |
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caption="3b7o, resolution 1.60Å" /> | caption="3b7o, resolution 1.60Å" /> | ||
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''<br /> | '''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''<br /> | ||
+ | |||
+ | ==Disease== | ||
+ | Known diseases associated with this structure: Leopard syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Leukemia, juvenile myelomonocytic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Noonan syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
- | [[Category: Arrowsmith, C | + | [[Category: Arrowsmith, C H.]] |
[[Category: Barr, A.]] | [[Category: Barr, A.]] | ||
- | [[Category: Delft, F | + | [[Category: Delft, F von.]] |
- | [[Category: Edwards, A | + | [[Category: Edwards, A M.]] |
[[Category: Elkins, J.]] | [[Category: Elkins, J.]] | ||
[[Category: King, O.]] | [[Category: King, O.]] | ||
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[[Category: Niesen, F.]] | [[Category: Niesen, F.]] | ||
[[Category: Patel, A.]] | [[Category: Patel, A.]] | ||
- | [[Category: Pilka, E | + | [[Category: Pilka, E S.]] |
- | [[Category: SGC, Structural | + | [[Category: SGC, Structural Genomics Consortium.]] |
[[Category: Salah, E.]] | [[Category: Salah, E.]] | ||
[[Category: Savitsky, P.]] | [[Category: Savitsky, P.]] | ||
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[[Category: tyrosine phosphatase]] | [[Category: tyrosine phosphatase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:03:55 2008'' |
Revision as of 17:03, 21 February 2008
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Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
Disease
Known diseases associated with this structure: Leopard syndrome OMIM:[176876], Leukemia, juvenile myelomonocytic OMIM:[176876], Noonan syndrome 1 OMIM:[176876]
About this Structure
3B7O is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Protein-tyrosine-phosphatase, with EC number 3.1.3.48 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 19:03:55 2008
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Single protein | Arrowsmith, C H. | Barr, A. | Delft, F von. | Edwards, A M. | Elkins, J. | King, O. | Knapp, S. | Niesen, F. | Patel, A. | Pilka, E S. | SGC, Structural Genomics Consortium. | Salah, E. | Savitsky, P. | Ugochukwu, E. | Weigelt, J. | MLT | Alternative splicing | Cytoplasm | Deafness | Disease mutation | Hydrolase | Phosphorylation | Protein phosphatase | Ptpn11 | Sgc | Sh2 domain | Shp2 | Structural genomics | Structural genomics consortium | Tyrosine phosphatase