3l9h

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[[Image:3l9h.png|left|200px]]
[[Image:3l9h.png|left|200px]]
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{{STRUCTURE_3l9h| PDB=3l9h | SCENE= }}
{{STRUCTURE_3l9h| PDB=3l9h | SCENE= }}
===X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085===
===X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085===
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{{ABSTRACT_PUBMED_20149654}}
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==See Also==
==See Also==
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*[[Kinesin]]
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*[[Kinesin|Kinesin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20149654</ref><references group="xtra"/>
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<ref group="xtra">PMID:020149654</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Knoechel, T.]]
[[Category: Knoechel, T.]]
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[[Category: Acetylation]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell division]]
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[[Category: Coiled coil]]
 
[[Category: Eg5]]
[[Category: Eg5]]
[[Category: Emd 534085]]
[[Category: Emd 534085]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Small molecule inhibitor]]
[[Category: Small molecule inhibitor]]

Revision as of 10:04, 25 July 2012

Template:STRUCTURE 3l9h

Contents

X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085

Template:ABSTRACT PUBMED 20149654

About this Structure

3l9h is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Schiemann K, Finsinger D, Zenke F, Amendt C, Knochel T, Bruge D, Buchstaller HP, Emde U, Stahle W, Anzali S. The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1491-5. Epub 2010 Jan 25. PMID:20149654 doi:10.1016/j.bmcl.2010.01.110

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