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2g70
From Proteopedia
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[[Image:2g70.png|left|200px]] | [[Image:2g70.png|left|200px]] | ||
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{{STRUCTURE_2g70| PDB=2g70 | SCENE= }} | {{STRUCTURE_2g70| PDB=2g70 | SCENE= }} | ||
===Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)=== | ===Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Phenylethanolamine N-methyltransferase]] | + | *[[Phenylethanolamine N-methyltransferase|Phenylethanolamine N-methyltransferase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017845018</ref><ref group="xtra">PMID:016710295</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylethanolamine N-methyltransferase]] | [[Category: Phenylethanolamine N-methyltransferase]] | ||
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[[Category: Tyndall, J D.A.]] | [[Category: Tyndall, J D.A.]] | ||
[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
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Revision as of 17:03, 25 July 2012
Contents |
Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)
Template:ABSTRACT PUBMED 17845018
About this Structure
2g70 is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385
- Lu J, Edwards RA, Wong JJ, Manchak J, Scott PG, Frost LS, Glover JN. Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM. EMBO J. 2006 Jun 21;25(12):2930-9. Epub 2006 May 18. PMID:16710295
