2rgr
From Proteopedia
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[[Image:2rgr.png|left|200px]] | [[Image:2rgr.png|left|200px]] | ||
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{{STRUCTURE_2rgr| PDB=2rgr | SCENE= }} | {{STRUCTURE_2rgr| PDB=2rgr | SCENE= }} | ||
===Topoisomerase IIA bound to G-segment DNA=== | ===Topoisomerase IIA bound to G-segment DNA=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Topoisomerase]] | + | *[[Topoisomerase|Topoisomerase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018097402</ref><ref group="xtra">PMID:020686482</ref><references group="xtra"/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Berger, J M.]] | [[Category: Berger, J M.]] | ||
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[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| - | [[Category: Isomerase | + | [[Category: Isomerase-dna complex]] |
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
Revision as of 11:28, 27 July 2012
Contents |
Topoisomerase IIA bound to G-segment DNA
Template:ABSTRACT PUBMED 18097402
About this Structure
2rgr is a 3 chain structure of Topoisomerase with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Dong KC, Berger JM. Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature. 2007 Dec 20;450(7173):1201-5. PMID:18097402 doi:10.1038/nature06396
- Bax BD, Chan PF, Eggleston DS, Fosberry A, Gentry DR, Gorrec F, Giordano I, Hann MM, Hennessy A, Hibbs M, Huang J, Jones E, Jones J, Brown KK, Lewis CJ, May EW, Saunders MR, Singh O, Spitzfaden CE, Shen C, Shillings A, Theobald AJ, Wohlkonig A, Pearson ND, Gwynn MN. Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature. 2010 Aug 19;466(7309):935-40. Epub 2010 Aug 4. PMID:20686482 doi:10.1038/nature09197
