1no9
From Proteopedia
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[[Image:1no9.png|left|200px]] | [[Image:1no9.png|left|200px]] | ||
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{{STRUCTURE_1no9| PDB=1no9 | SCENE= }} | {{STRUCTURE_1no9| PDB=1no9 | SCENE= }} | ||
===Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.=== | ===Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.=== | ||
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{{ABSTRACT_PUBMED_12885234}} | {{ABSTRACT_PUBMED_12885234}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[1no9]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NO9 OCA]. | + | [[1no9]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NO9 OCA]. |
==See Also== | ==See Also== | ||
- | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
+ | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012885234</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
+ | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: N-diphenylcarbamoyl-aminoguanidine]] | [[Category: N-diphenylcarbamoyl-aminoguanidine]] | ||
[[Category: Serine proteinase inhibition]] | [[Category: Serine proteinase inhibition]] |
Revision as of 17:46, 25 July 2012
Contents |
Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.
Template:ABSTRACT PUBMED 12885234
About this Structure
1no9 is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT. Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies. Biochemistry. 2003 Aug 5;42(30):9013-21. PMID:12885234 doi:10.1021/bi020512l