2a45
From Proteopedia
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[[Image:2a45.png|left|200px]] | [[Image:2a45.png|left|200px]] | ||
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{{STRUCTURE_2a45| PDB=2a45 | SCENE= }} | {{STRUCTURE_2a45| PDB=2a45 | SCENE= }} | ||
===Crystal structure of the complex between thrombin and the central "E" region of fibrin=== | ===Crystal structure of the complex between thrombin and the central "E" region of fibrin=== | ||
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{{ABSTRACT_PUBMED_16533041}} | {{ABSTRACT_PUBMED_16533041}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2a45]] is a | + | [[2a45]] is a 10 chain structure of [[Fibrinogen]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1qvh 1qvh]. The November 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fibrin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_11 10.2210/rcsb_pdb/mom_2006_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A45 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Fibrinogen]] | + | *[[Fibrinogen|Fibrinogen]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016533041</ref><ref group="xtra">PMID:014978285</ref><references group="xtra"/> |
[[Category: Fibrin]] | [[Category: Fibrin]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Fibrin]] | [[Category: Fibrin]] | ||
[[Category: Fragment e]] | [[Category: Fragment e]] | ||
| - | [[Category: | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Thrombin-fibrin complex]] | [[Category: Thrombin-fibrin complex]] | ||
Revision as of 17:58, 25 July 2012
Contents |
Crystal structure of the complex between thrombin and the central "E" region of fibrin
Template:ABSTRACT PUBMED 16533041
About this Structure
2a45 is a 10 chain structure of Fibrinogen and Thrombin with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1qvh. The November 2006 RCSB PDB Molecule of the Month feature on Fibrin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_11. Full crystallographic information is available from OCA.
See Also
Reference
- Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L. Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:16533041 doi:10.1021/bi0525369
- Pechik I, Madrazo J, Mosesson MW, Hernandez I, Gilliland GL, Medved L. Crystal structure of the complex between thrombin and the central "E" region of fibrin. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2718-23. Epub 2004 Feb 20. PMID:14978285 doi:10.1073/pnas.0303440101
