1rt3
From Proteopedia
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[[Image:1rt3.png|left|200px]] | [[Image:1rt3.png|left|200px]] | ||
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{{STRUCTURE_1rt3| PDB=1rt3 | SCENE= }} | {{STRUCTURE_1rt3| PDB=1rt3 | SCENE= }} | ||
===AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91=== | ===AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Reverse transcriptase]] | + | *[[Reverse transcriptase|Reverse transcriptase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009689112</ref><ref group="xtra">PMID:015084137</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] | ||
Revision as of 01:17, 26 July 2012
Contents |
AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91
Template:ABSTRACT PUBMED 9689112
About this Structure
1rt3 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK. 3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9518-23. PMID:9689112
- Udier-Blagovic M, Tirado-Rives J, Jorgensen WL. Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. J Med Chem. 2004 Apr 22;47(9):2389-92. PMID:15084137 doi:10.1021/jm0303507
