3c09

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Revision as of 21:51, 26 December 2010

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Template:STRUCTURE 3c09

Contents 1 Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR 2 About this Structure 3 See Also 4 Reference

Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR

Template:ABSTRACT PUBMED 18394559

About this Structure

3c09 is a 6 chain structure of Epidermal Growth Factor Receptor and Monoclonal Antibody with sequence from Homo sapiens and Homo sapiens, mus musculus. Full crystallographic information is available from OCA.

See Also

• Epidermal Growth Factor Receptor
• Monoclonal Antibody

Reference

• Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell. 2008 Apr;13(4):365-73. PMID:18394559 doi:10.1016/j.ccr.2008.02.019