2wxl

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Revision as of 21:54, 26 December 2010

Template:STRUCTURE 2wxl

Contents

THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH ZSTK474.

Template:ABSTRACT PUBMED 20081827

About this Structure

2wxl is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Ruckle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol. 2010 Feb;6(2):117-24. PMID:20081827 doi:10.1038/nchembio.293

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